We are in relentless pursuit of breakthroughs that change patients' lives. We create innovations daily to make the world a better place. This was Charles Pfizer's original vision, and it holds true today. Research confirms what we instinctively know: that purpose-driven companies deliver better results, are more innovative, draw and keep the best professionals, and know how to harness the power of those team members. Pfizer's purpose—Breakthroughs that transform patients' lives—powers everything we do and demonstrates our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and embodies the value we work to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We fulfill our purpose by sourcing the best science in the world, collaborating with others in the healthcare system to enhance access to our medicines, utilizing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.